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Miskatonic University is an institution of higher learning located in Arkham, Massachussetts. It became known outside academic circles mostly through the horror stories of H.P. Lovecraft. Popularly supposed to be fictional, it is - just like other legendary places that have become bywords, like Timbuctoo or Ruritania - a real establishment, locatable on any map.

Philip José Farmer identified one of its faculty as Professor William Harper "Johnny" Littlejohn, best known as an associate of Doc Savage, and further said that Professor Littlejohn had taken part in the University's Antarctic Expedition in 1929 as described by Lovecraft in the novel At the Mountains of Madness.

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